LBgard® Blood Tubes

Robust cfDNA collection for liquid biopsy and NIPT

  • Preserve cfDNA for 14 days
  • Preserve CTCs and WBCs for 4 days
  • Minimize hemolysis & gDNA release
  • Secure blood samples in plastic tubes
LBgard Blood Tube

Workflow Overview

LBgard Workflow
For Research Use Only. Not for use in diagnostic procedures.

Product Data

LBgard Blood minimizes genomic DNA release in healthy donor blood

Bioanalyzer data at 4, 25, and 37 degrees C
Figure 1: Genomic DNA release is minimized (Bioanalyzer traces in left panels, black arrows) and plasma DNA concentration is maintained (fold change in plasma DNA concentration from Day 0 to Day 7 and Day 14 as measured by Quant-iT™ dsDNA Assay Kit in right panels) by LBgard Blood tubes over 14 days at 4°C, 25°C, and 37°C. Blood was collected in Streck cfDNA BCT or LBgard Blood tubes and stored at the indicated temperatures and time points prior to plasma collection.

Plasma DNA concentration maintained by LBgard Blood over 7 days at 25°C

Table showing Plasma DNA concentration is maintained by LBgard™ Blood tubes over 7 days at 25°C
Table 1: Plasma DNA concentration is maintained by LBgard Blood over 7 days at 25°C. Data obtained from healthy donor blood samples and measured by Quant-iT™ assay.

LBgard Blood minimizes genomic DNA release in colorectal cancer donor blood

Data showing genomic DNA release in LBgard™ Blood tubes compared to Streck cfDNA BCT from samples from stage IV colorectal cancer (CRC) patients
Figure 2: Genomic DNA release is controlled by LBgard Blood compared to Streck cfDNA BCT in samples from stage IV colorectal cancer (CRC) patients. A representative Bioanalyzer trace from one patient is shown (Top). cfDNA yield in ng/ml plasma for 3 clinical samples.

LBgard Blood maintains fractional abundance of mutant allele over 7 days

Data showing fractional abundance of KRASG12D is maintained by LBgard™ Blood tubes over 7 days at 25°C as measured by droplet digital PCR.
Figure 3: The fractional abundance of KRASG12D is maintained by LBgard Blood over 7 days at 25°C as measured by droplet digital PCR.

LBgard Blood minimizes hemolysis

Data showing LBgard controlling hemolysis in blood samples for 7 days at 25 degrees C.
Figure 4:LBgard Blood controls hemolysis in blood samples for 7 days at 25°C.

LBgard Blood provides superior CTC and WBC recovery

Data showing VCaP cells and WBCs are recovered at 98% and 90% respectively, in LBgard Blood tubes over 4 days at 25 degrees C
Figure 5:VCaP prostate cancer cells spiked into whole blood are preserved by LBgard Blood. VCaP cells (left) and WBCs (right) are recovered at 98% and 90% respectively, in LBgard Blood tubes over 4 days at 25°C.

LBgard Blood maintains cell morphology and protein biomarker expression

Data showing Cell morphology and protein biomarker expression are preserved in both WBC (CD45) and spiked VCaP cells (EpCAM) for 4 days at 2 degrees C.
Figure 6:Cell morphology and protein biomarker expression are preserved in both WBC (CD45) and spiked VCaP cells (EpCAM) in LBgard Blood for 4 days at 25°C.

Product Specifications

Product description: Evacuated, sterile, blood collection tubes (10mL)
Pre-fill volume (preservative) = 0.6mL
Blood draw volume = 8.5mL
Pre-fill storage temperature = 4°C - 25°C
Post-fill storage temperatures:
• cfDNA = 14 days at 4°C - 37°C
• CTCs and WBCs = 4 days at 18°C - 30°C

Ordering

Catalog No. Product Description Size Price
68021-001 LBgard® Blood Tubes 50 tubes $400.00

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