Biomarker Collection and Preservation for Diagnostics
Chemical Preservation of Reagents in Kits and Cartridges
Biomatrica has developed a range of products for forensic scientists in biological evidence collection, transportation, storage, and processing. DNA extracts from different sample types (blood, semen, buccal, etc) can be preserved for long-time at room temperature with high quality and high yield. Our room temperature DNA stabilization reagents as well as assay enhancement products (see below) have been well validated by several forensic scientists and laboratories. A detailed listing of these validations and publications is also provided below.
DNAstable® enables you to preserve, store and ship your purified DNA samples at room temperature. Sample recovery is achieved within minutes by simply adding water or buffer to the matrix. Sample is ready for downstream analysis without need for any additional purification step.
Pre-dried in tubes or plates (DNAstable)
Liquid-to-Dry storage format (DNAstable LD)
To learn more about DNAstable, or to place an order, please click here.
PCRboost® is a reagent that enhances end-point and reverse
transcription-PCR performance by improving sensitivity and specificity
during amplification of genomic DNA or RNA templates.
To learn more about PCRboost, or to place an order, please click here.
Summary of Biomatrica Technologies, Key Customers and Customer Publications for the Forensic Community
Long-term storage of gDNA in DNAstable.
DNA extracts from 3 different sample types - blood, semen and buccal cells were stored dry in DNAstable at room temperature as well as frozen at -20C (control) for 45 months. After rehydration (DNAstable-matrix) and freeze/thaw (cold-frozen), the recovery and STR profiles of the samples were determined. STR profile results show no allelic drop-outs in all samples stored frozen or at ambient temperatures over 45 months. Higher DNA recovery were observed for DNAstable-stored samples over frozen samples as displayed below.
Details of the study are reported in an application note.
A Forensic DNA workshop was conducted at the 2011 AAFS Meeting, with presentations from four crime labs:
Download all presentations here
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